Available translations

Equine 74 products support equine wellbeing.

Alleviate symptoms

Achieve noticeable results

Demonstrate significant effectiveness

Is there an alternative to omeprazole in horses?

Tanja Dietz


11 Min. Lesezeit

Audio version – listen to this article easily

"I have really tried everything with my horse with gastric ulcers" or "I don't want to give my horse permanent medication against his gastric ulcers" are statements we hear again and again. For many horse owners, the treatment of a gastric ulcer is time-consuming and expensive, because preparations such as omeprazole are expensive. Are you, as a horse owner, looking for an alternative for a variety of reasons? You will find it here!  

Secure a free feed sample of Equine 74 Gastric and help your horse to buffer  excess stomach acid, so it feels well again.

Are you interested in specific questions? Then click here to get directly to the chapter:

How is the horse's stomach structured?

In order to achieve effective treatment of gastric ulcers, a little prior knowledge about the anatomy of the horse's gastric is required. The single-cavity gastric is quite small in relation to the horse's body size and holds only up to 15 litres. The entrance to the gastric (cardia) connects the oesophagus with the gastric. The horse's gastric belongs to the group of compound stomachs. The reason for this is the differentiation into two parts - the upper part with a squamous mucosa and the lower part with a glandular mucosa. The margo plicatus separates the two areas from each other in the form of a border line. The stomach outlet is called the pylorus and connects the stomach with the small intestine. 



The upper, squamous part of the stomach contains no mucus-secreting glands that could form a protective layer against stomach acid. Therefore, the sensitive mucous membrane is particularly affected by an excess of gastric acid. If gastric acid reaches the gastric wall, this can lead to irritations, so-called lesions, within a very short time. Within 24 to 48 hours, irritation of the mucous membrane can develop into a crater-shaped gastric ulcer. The Latin term “ulcer” translates as "deep defect of the skin".   

Although ulcers occur less frequently in the glandular part, they should not be disregarded, especially since the causes are often even more difficult to fathom here, since gastric acid is permanently present and can be ruled out as the only trigger. 

Where do stomach ulcers develop in horses?

Before a gastric ulcer develops, an irritation of the stomach mucosa precedes it. The term Equine Gastric Ulcer Syndrome (EGUS) covers all lesions. A distinction is then made between Equine Squamous Gastric Disease (ESGD, ulcers of the non-glandular mucosa) and Equine Glandular Gastric Disease (EGGD gastric ulcers of the glandular mucosa). They can occur separately and together. 

In order to be able to select a suitable medication or supplement for the horse's gastric, an exact diagnosis is required, because ESGD and EGGD are not only different in their cause but also in the treatment methods. 

Causes for gastric ulcers in the squamous part are often feed-related, whereas the cause for ulcers in the glandular mucosa is often stress. Ulcers at the Pylorus can be the result of mechanical irritation by feed such as alfalfa, but can also be caused by a backflow of predigested food from the small intestine. 

Only a gastroscopy can provide information about the severity and localisation of the mucosal irritation or gastric ulcer. The lesions are classified according to their severity using the ulcer score (0-4). Depending on the diagnosis, the treatment method is then recommended by a veterinarian.

What influence do husbandry and feeding have on the development of gastric ulcers in horses?

The causes of gastric ulcers are manifold - they can be caused by wrong feeding or bad husbandry, be a consequence of longterm-medication or occur due to stress. The assumption that only competition horses suffer from stomach ulcers is wrong. Approximately 40 % of leisure horses and 50 % of foals are also affected.

Horses are evolutionarily continuous eaters, and their stomachs are designed for this and are prepared to continuously consume small amounts of roughage. For this reason, gastric acid (HCl) is permanently produced so that the digestion process does not come to a halt.

continuously consume small amounts of roughage equine74


This is a big difference to the natural gastric acid buffer bicarbonate. This is found in the horse's saliva, which is secreted just during the chewing process. In the wild, where constant grazing was guaranteed, horses produced enough saliva so that bicarbonate and stomach acid were naturally in balance. 

Nowadays, the husbandry and feeding of horses has changed a lot. Less free movement and small amounts of roughage as well as irregular feeding times, intensive training, unloved box neighbours, a heterogeneous group composition on the pasture and much more can cause stress for some horses. 

Stress - the trigger for stomach ulcers?

Veterinarians often say that stress-related overproduction of gastric acid is the main cause for a gastric ulcer. Gastric acid per se is not a bad thing. The horse's stomach is dependent on gastric acid because it plays an important role in digestion. On the one hand, it moistens the food pulp and prepares the food for further digestion, and on the other hand, it also kills bacteria in the feed.

But as always, the dose makes the poison! The horse cannot handle with a permanent overproduction of stomach acid. If there is too much acid in the stomach, it spills around like a small lake and damages the squamous mucous membrane. Especially when trotting and cantering, horses show discomfort and signal pain. That is why you should never ride your horse on an empty stomach.

Stress has also another influence: the cortisol level is increased during stress, which leads to a reduced blood supply to the stomach lining, which thus has a reduced resistance and cannot regenerate quickly enough. An irritation of the gastric mucosa in turn causes the horse pain, which further stresses the horse. This creates a kind of vicious circle. Stress should therefore be avoided as much as possible in the horse's environment. 

3 Treatment options for gastric ulcers in horses

In addition to optimising husbandry, feeding and training, you can treat your horse with medication or support it with a supplement. Three types are distinguished here.


  1. Gastric acid buffers: Also called Antacids, these are alkaline substances that neutralise gastric acid that is already present. Neutralising means that the pH value in the stomach is raised and is therefore no longer so acidic. Equine 74 Gastric belongs to this group. 

  2. Gastric acid blockers: They have the ability to block the production of gastric acid by inhibiting the proton pump of the occupant cells in the stomach. As a result, up to 99 % less stomach acid is produced, giving the damaged mucous membrane time to regenerate. 

  3. Gastric protectors: They form a layer on the mucous membrane and protect the stomach wall from acid. Feed supplements based on pectins and lecithin are particularly suitable for this purpose, as they support the natural protective mechanisms of the stomach lining. The same applies to linseed, which contains a particularly high amount of mucilage. Some feeds can also support your horse's recovery. Find out here which ones are particularly suitable.  

Diagnosis of gastric ulcer in a horse - What’ next?

Your horse has been behaving strangely in the past, got a dull coat and stopped eating its hay, so you contacted your vet. Using an endoscope, he made a gastroscopy and was able to identify gastric ulcers in the non-glandular part of the stomach. In this localisation of the gastric omeprazole is recommended for the horse in many cases. 

How does omeprazole work in horses?

Acid-producing cells, such as the vestibular cells in the stomach, need protons, such as potassium and hydrogen, to produce pepsin and HCl. These substances are transported via a proton pump. The active ingredient omeprazole is a proton pump inhibitor and belongs to the group of stomach acid blockers.

The active ingredient inhibits the H+/K+-ATPase enzyme system, which acts as an acid-proton pump in the stomach mucosa. This inhibition of the proton pumps reduces gastric acid secretion by up to 99 %, so that the mucous membrane no longer comes into contact with HCl and has time to regenerate. Omeprazole cures can last several weeks, depending on the severity of the stomach ulcer. 

When is omeprazole useful?

In acute, bleeding gastric ulcers in the squamous part of the stomach, the use of omeprazole is absolutely recommended. In order to document the healing process of a gastric ulcer, a control gastroscopy is useful. A gastroscopy is stressful for many horses, as long periods of fasting are a prerequisite for an effective examination. Talk to your vet about the pros and cons of gastroscopys and when a follow-up is appropriate. 

In addition to the endoscopic imaging procedure, you should also monitor your horse closely for any improvement in symptoms. Premature discontinuation of omeprazole can lead to a relapse. 

What happens after a omeprazole treatment in horses? 

To prevent a relapse after the omeprazole cure, you as a horse owner should take precautions and look for a long-term solution, because medication should not be a permanent solution.

The risk of getting a gastric ulcer again can never be reduced to 0 %, but you can take some prophylactic measures. Especially husbandry and feeding have a great influence on the health of your horse.

3 important tips to prevent stomach ulcers in horses


3 Tips Abbildung Blog Nr. 2

3 Tips Abbildung Blog Nr. 1

3 Tips Abbildung Blog Nr. 3


If you are in a boarding stable, some aspects are certainly out of your hands, such as roughage feeding. However, as a horse owner, you can start with small things. You have a great influence on your horse. If you come to the stable stressed, this will also affect your horse. So start with yourself and create a more relaxed atmosphere in the stable and while riding. 


In order to draw attention to the topic of the horse's stomach health, it is a good idea to talk about it in the stable aisle and to sensitise not only stable colleagues but also the stable owner, because in the end the welfare of the horses always has the highest priority. 

The topic of stress prevention is really important if you want to prevent a relapse in your horse. However, since stressors can never be completely avoided, it can be helpful to buffer excess gastric acid, e.g. with a gastric supplement.

Equine 74 Gastric as a long-term alternative to omeprazole

In the case of acute, bloody gastric ulcers, the administration of preparations containing omeprazole is recommended. This gives the mucous membrane the opportunity to regenerate. If you want to switch to a natural supplement like Equine 74 Gastric, it is important to phase out omeprazole. This way, the stomach slowly gets used to the production of gastric acid again.

We recommend that our customers start feeding Equine 74 Gastric about two weeks before they plan to stop taking omeprazole. For this purpose, a dosage of one teaspoon of Equine 74 Gastric should be started. Until omeprazole is discontinued, the amount of Equine 74 Gastric can then be increased to the recommended amount of 50 g per day (500 kg warm-blooded horse). It is best to divide the feeding into two to three rations per day. If this is not possible, we recommend feeding before the longest feeding break, which is usually in the evening. 

To avoid a relapse after a course of omeprazole, a stomach supplement should be fed for support during the transition. Equine 74 Gastric can be used both as a 6-week cure and as a permanent part of the feeding routine. In order to achieve lasting therapeutic success, the primary cause must be eliminated. 

Why is Equine 74 Gastric the right gastric supplement for my horse?

Are you looking for a long-term solution that is free of chemicals and cost-intensive medication? 

Equine 74 Gastric is based on red algae harvested off the coast of Iceland, which counteracts the excess acidity in the horse's stomach caused by feeding and stress. The organically certified formula is characterised by a high bioavailable calcium content. This increases the acid buffering capacity, which is 2.5 times higher than comparable limestones and thus binds stomach acid. Equine 74 Gastric is a gastric acid buffer that only binds the excess stomach acid so that the stomach acid needed for the digestive processes is still present. In this way, the pH value in your horse's gastric becomes more and more balanced. 

The advantages of Equine 74 Gastric at a glance

  • 2.5 times higher acid buffering capacity than supplements derived from limestone
  • Large amounts of highly bioavailable calcium and magnesium released in the horse's gastric
  • Special sponge structure with a large surface area which is slowly decomposed in the horse's stomach so that the stomach acid can be buffered over a longer period of time
  • The function of the gastric acid is maintained
  • Available in three variants (powder, pellet, granulate)
  • Doping-free
  • 100 % natural
  • Subscription only €52 per month (€1.73 per day)

Equine 74 Gastric

The long-term solution

Buffers the excess acid in the horse's stomach instead of blocking it.

Equine 74 Stomach Calm Relax

In case of acute stress

Supports the nervous horse stomach in stressful situations.